Typhi Dot Duo (IgM & IgG) Test – PK101
🩸 Comprehensive Typhoid PanelReport: Same Day
Sample Type: Blood (Serum)
Test Code: PK101
The Typhi Dot Duo (IgM & IgG) Test is a comprehensive serological panel that detects both "early" (IgM) and "memory" (IgG) antibodies against the Typhoid bacterium, Salmonella typhi. By measuring both antibodies from a single blood sample, this test provides a clearer picture of the infection timeline.
✔ Helps differentiate between an acute/current infection and a past infection.
✔ Offers a more complete diagnostic insight than either test alone.
✔ Ideal for patients with a prolonged fever to understand the stage of the illness.
✔ Convenient and cost-effective package with same-day reporting.
A Complete Picture: Why Test for Both IgM & IgG?
When diagnosing Typhoid fever, understanding the timing of the infection is crucial. Is it a new, active infection that needs immediate antibiotic treatment, or is it evidence of an old infection that the body has already fought off? Testing for a single antibody can sometimes be ambiguous. The Typhi Dot Duo package removes this ambiguity by measuring both IgM and IgG simultaneously.
- IgM Antibodies: These are the "first responders." Their presence indicates a current, active infection, as they are the first to be produced by the immune system.
- IgG Antibodies: These are the "memory" antibodies. They appear later in the infection and can persist for years, indicating a past infection or a later stage of a current one.
Interpreting the Combined Results
By looking at the results of both tests together, your doctor can make a much more accurate assessment of your condition:
IgM POSITIVE / IgG NEGATIVE:
Strongly indicates an early, acute Typhoid infection.
IgM POSITIVE / IgG POSITIVE:
Suggests an active infection in a later stage, or a possible recent reinfection.
IgM NEGATIVE / IgG POSITIVE:
Indicates a past infection or the late recovery (convalescent) phase. The active infection is likely over.
IgM NEGATIVE / IgG NEGATIVE:
No serological evidence of a recent or past infection. Typhoid is unlikely, unless it is a very early infection before antibodies have formed.
This comprehensive approach provides your doctor with the clear, actionable information needed for a confident diagnosis and treatment plan.
Frequently Asked Questions (FAQ)
The Duo test provides a complete timeline of the infection. It helps your doctor clearly distinguish between a brand new, active infection that needs immediate treatment and an old infection from the past, which prevents diagnostic confusion.
This usually means you are in the middle or later stage of an active infection. Your body has produced the initial IgM antibodies, and is now also producing the long-term IgG antibodies. It could also indicate a recent reinfection in a person who has had typhoid before.
This typically means you have had a typhoid infection in the past and your body has retained an "immune memory" of it. It does not usually indicate a current, active illness that requires treatment.
This package is an excellent and rapid diagnostic tool. However, the "gold standard" for a definitive diagnosis, especially in the first week of fever, is a Blood Culture test. The Typhi Dot Duo is often used alongside clinical symptoms for a rapid and reliable diagnosis.
No. A single blood sample is sufficient for both tests, and no fasting is required.