MYCOBACTERIUM TUBERCULOSIS DNA PCR (QUALITATIVE) – MC044
🦠 Rapid TB Diagnosis📋 Test Details
- Report Time: Next Day Evening.
- Method: Real-Time PCR (Polymerase Chain Reaction).
- Sample Type: Sputum, Body Fluids, Pus, Urine, Tissue, or EDTA Blood.
- Test Code: MC044
What is the TB DNA PCR Test?
This is a highly sensitive molecular test used to detect the DNA of Mycobacterium tuberculosis (the bacteria that causes TB) in a patient sample. Unlike traditional tests that look for the bacteria itself (which can be hard to find), this test looks for the bacteria's genetic material.
Because PCR multiplies tiny amounts of DNA millions of times, it can detect TB even when the bacterial count is very low (Paucibacillary TB), making it far more accurate than a standard sputum smear microscopy.
Why Choose PCR over Routine Tests?
Traditional TB Cultures can take 4-8 weeks to show results. PCR gives a confirmed diagnosis by the next evening, allowing treatment to start immediately.
It can detect TB in Smear Negative cases (where the routine microscope test says negative, but the patient is actually infected).
It can be performed on almost any sample: Sputum (Lung TB), Pleural Fluid, Urine (Kidney TB), Pus, or Tissue Biopsies.
Understanding the Results
- Detected (Positive): Mycobacterium tuberculosis DNA is present. Active infection is confirmed.
- Not Detected (Negative): DNA is not found. However, clinical correlation is advised if symptoms persist.
Frequently Asked Questions
No. PCR detects the DNA of the bacteria directly from the site of infection. It is primarily for diagnosing Active Tuberculosis.
Yes, but blood (EDTA) is only useful for Disseminated TB (when TB has spread throughout the body). For Lung TB, Sputum is always the best sample.
No. This is a Qualitative test (Yes/No). To check for drug resistance (MDR-TB), you would need a specialized test like GeneXpert (CBNAAT) or Line Probe Assay.
Disclaimer: TB is a notifiable disease. Positive results should be correlated clinically and reported as per government guidelines.