PHOSPHOLIPID ANTIBODY (APLA) IgA – ES125
🩸 Clotting & Pregnancy Risk
₹499
MRP ₹750
Sample Time: 4:30 PM
Report: Same Day
Sample Type: Blood (Serum)
Test Code: ES125
Report: Same Day
Sample Type: Blood (Serum)
Test Code: ES125
About this Test:
The Phospholipid Antibody (APLA) IgA test detects a specific type of autoantibody that attacks phospholipids (part of cell membranes). The presence of these antibodies increases the risk of excessive blood clotting.
✔ Helps diagnose Antiphospholipid Syndrome (APS), especially when IgG/IgM tests are negative.
✔ Crucial for investigating the cause of recurrent miscarriages or pregnancy complications.
✔ Used to determine the cause of unexplained thrombosis (blood clots) or stroke.
✔ Useful in patients with Systemic Lupus Erythematosus (SLE).
The Phospholipid Antibody (APLA) IgA test detects a specific type of autoantibody that attacks phospholipids (part of cell membranes). The presence of these antibodies increases the risk of excessive blood clotting.
✔ Helps diagnose Antiphospholipid Syndrome (APS), especially when IgG/IgM tests are negative.
✔ Crucial for investigating the cause of recurrent miscarriages or pregnancy complications.
✔ Used to determine the cause of unexplained thrombosis (blood clots) or stroke.
✔ Useful in patients with Systemic Lupus Erythematosus (SLE).
Understanding APLA and the Role of IgA
Antiphospholipid Syndrome (APS) is an autoimmune disorder where the body makes antibodies that mistakenly attack phospholipids a type of fat found in all living cells, including blood cells and the lining of blood vessels. This attack makes the blood sticky and more likely to clot.
Why Test for IgA specifically?
Standard screening for APS usually checks for IgG and IgM antibodies first. However, some patients have all the clinical symptoms of the syndrome (clots, miscarriages) but test negative for IgG and IgM. This is where the IgA test is vital.
- Seronegative APS: IgA antibodies may be the only marker present in some patients. Detecting them prevents a missed diagnosis.
- SLE Association: IgA antiphospholipid antibodies are frequently found in patients with Lupus (SLE) and are linked to specific complications like skin ulcers or thrombocytopenia.
- Pregnancy Risk: Like other APLA types, IgA antibodies can interfere with placental blood flow, leading to risks like preeclampsia or fetal loss.
Frequently Asked Questions (FAQ)
Q1: What is Antiphospholipid Syndrome (APS)?
APS is an autoimmune disorder that causes an increased risk of forming blood clots in arteries and veins. It is also a major cause of pregnancy complications like miscarriage and stillbirth.
APS is an autoimmune disorder that causes an increased risk of forming blood clots in arteries and veins. It is also a major cause of pregnancy complications like miscarriage and stillbirth.
Q2: Why did my doctor order the IgA test?
Your doctor likely ordered this because you have symptoms of a clotting disorder or history of pregnancy loss, but other standard tests (IgG/IgM) might have been negative or inconclusive. The IgA test ensures a diagnosis isn't missed.
Your doctor likely ordered this because you have symptoms of a clotting disorder or history of pregnancy loss, but other standard tests (IgG/IgM) might have been negative or inconclusive. The IgA test ensures a diagnosis isn't missed.
Q3: What does a positive result mean?
A positive result suggests the presence of autoantibodies that increase your risk of blood clots. However, a diagnosis of APS usually requires the test to be positive on two separate occasions, at least 12 weeks apart, to rule out temporary infections.
A positive result suggests the presence of autoantibodies that increase your risk of blood clots. However, a diagnosis of APS usually requires the test to be positive on two separate occasions, at least 12 weeks apart, to rule out temporary infections.
Q4: Do I need to fast for this test?
No, fasting is generally not required for the APLA IgA blood test.
No, fasting is generally not required for the APLA IgA blood test.
Q5: Can this test help with pregnancy planning?
Yes. If you have a history of miscarriage, this test helps identify if an autoimmune clotting issue is the cause. If positive, doctors can prescribe blood thinners (like aspirin or heparin) to support a successful pregnancy.
Yes. If you have a history of miscarriage, this test helps identify if an autoimmune clotting issue is the cause. If positive, doctors can prescribe blood thinners (like aspirin or heparin) to support a successful pregnancy.